Is QuantiFERON gold specific?

QFT-Plus is a highly accurate test with >97% specificity for detection of TB infection.

How accurate is QuantiFERON gold test?

The specificity of QuantiFERON-TB Gold has consistently shown to be >99% in low risk individuals (12). Specificity is the probability that the test indicates a person does not have the disease (or infection) when that person is disease free.

Why is QuantiFERON gold indeterminate?

The indeterminate test results may be due to possible immunosuppression or due to some technical errors and is indicated by low mitogen response. The advanced age and underlying disease in patients receiving immunosuppressive treatment comprise the risk factors that can promote indeterminate results on QFT-G test.

What can causes a false positive QuantiFERON gold?

(1) False-positive results may occur in patients with prior infection with M marinum, M szulgai, or M kansasii. Negative: No IFN-gamma response to M tuberculosis antigens was detected. Infection with M tuberculosis is unlikely.

What does high mitogen nil mean?

The Mitogen minus Nil value serves as the positive control, demonstrating the successful responsiveness of the T lymphocytes in patient specimen. A negative result suggests that M. tuberculosis infection is unlikely.

Is QuantiFERON the same as TB test?

QuantiFERON-TB Gold (QFT) is a simple blood test that aids in the detection of Mycobacterium tuberculosis, the bacteria which causes tuberculosis (TB). QFT is an interferon-gamma (IFN-γ) release assay, commonly known as an IGRA, and is a modern alternative to the tuberculin skin test (TST, PPD or Mantoux).

Is QuantiFERON TB Gold same as IGRA?

Is t spot a blood test?

TB test is a unique, single visit blood test for tuberculosis designed to reduce assay variability and maximize sensitivity, even in the immunocompromised.

What if TB Gold test is negative?

A positive test result suggests that M. tuberculosis infection is likely; a negative result suggests that infection is unlikely. An indeterminate result indicates an uncertain likelihood of M. tuberculosis infection.

Does BCG affect Quantiferon gold?

Unlike the TST, QFT is not affected by Bacille Calmette-Guérin (BCG) vaccination. You can lift the costly burden that inaccurate TB screening results place on your practice and on your patients.

How often is a Quantiferon false-positive?

In realistic settings of low risk of TB infection, even with high cutoffs and confirmation, the post-test probability of a positive QFT test on serial testing may still only approach 60%, while annual testing with a single QFT using the recommended diagnostic cutoff may cause over 25% of individuals to have a false- …

What is TB mitogen?

The mitogen tube also serves as a control for indicating long or improper transport, incorrect blood handling and incubation. If technical issues are suspected with the collection or handling of blood samples, repeat the entire QuantiFERON TB Gold Plus test with new blood specimens.

How long is Quantiferon Gold test results good for?

A healthcare practitioner will interpret a tuberculin skin test result by looking at the injection site on the person’s forearm at 48 or 72 hours (in most cases). A positive result will form a red and swollen raised circle at the site of the injection.

What does a positive gold test mean?

1 Answer. A positive tuberculin skin test or QuantiFERON ®- TB Gold test only tells that a person has been infected with TB germs. It does not tell whether or not the person has progressed to TB disease. Other tests, such as a chest x-ray and a sample of sputum, are needed to see whether the person has TB disease.

How is a Quantiferon Gold test performed?

How long does TB Gold test take?

Conservatively, QuantiFERON TB blood test results typically take approximately six business days to be reported. For many people in busy metropolitan areas, TB blood test results can be available in as soon as three business days.