What is Angiomyofibroblastoma?

What is Angiomyofibroblastoma?

Angiomyofibroblastoma (AMFB) is an uncommon benign mesenchymal tumor. AMFB occurs almost in the vulvo-vaginal area of women. The gross features of AMFB are well-circumscribed so it clinically is often thought as Bartholin gland cyst or aggressive angiomyxoma.

What is a superficial Angiomyxoma?

Superficial angiomyxomas (SA) of the skin are rare benign cutaneous tumors of soft tissue composed of prominent myxoid matrix and numerous blood vessels. SA are more common in males [1] and they are usually located on the trunk but can also appear on the lower limbs, head, neck and genitalia [2,3].

What is aggressive Angiomyxoma?

Aggressive angiomyxoma is a rare mesenchymal tumor that most commonly arises in the vulvovaginal region, perineum, and pelvis of women. The term aggressive emphasizes the often infiltrative nature of the tumor and its frequent association with local recurrence.

Is Angiomyxoma cancerous?

Angiomyxomas are a rare type of soft tissue tumour (lump). They are not thought of as cancer because they usually grow quite slowly and they don’t usually spread to other parts of the body.

What does a Angiomyxoma feel like?

The majority of patients present with a slow-growing mass which is otherwise asymptomatic and this is frequently the only symptom/sign. Observed accompanying symptoms and signs are regional pain, a feeling of local pressure, or dyspareunia. Tumour size is often underestimated by physical examination.

What is a myxoid neurofibroma?

Myxoid neurofibroma is a rare benign tumor derived from Schwann cells. Myxoid neurofibromas are slow growing and typically asymptomatic. They occur as solitary lesions and are rarely associated with neurofibromatosis. The pathogenesis of myxoid neurofibromas remains unknown.

What does myxoid mean?

Myxoid is a word pathologists use to describe connective tissue that looks more blue or purple compared to normal connective tissue when examined under the microscope. The type of connective tissue that usually shows myxoid type change is called the stroma.

What is a myxoid tumor?

A myxoid tumor is a connective tissue tumor with a “myxoid” background, composed of clear, mucoid substance.

How can you tell the difference between osteoid osteoma and osteoblastoma?

Histologically, osteoid osteoma and osteoblastoma are similar, containing osteoblasts that produce osteoid and woven bone. Osteoblastoma, however, is larger, tends to be more aggressive, and can undergo malignant transformation, whereas osteoid osteoma is small, benign, and self-limited.

Does osteoblastoma come back?

Osteoblastoma returns in approximately 10 to 20% of patients. The likelihood of the tumor recurring is related to how well it can be completely removed without causing damage to normal structures.

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