What is diphenhydramine HCL used for?

What is diphenhydramine HCL used for?

Diphenhydramine is used to relieve red, irritated, itchy, watery eyes; sneezing; and runny nose caused by hay fever, allergies, or the common cold. Diphenhydramine is also used to relieve cough caused by minor throat or airway irritation.

Is diphenhydramine a anticholinergic?

Diphenhydramine is a potent anticholinergic agent and potential deliriant in higher doses. This activity is responsible for the side effects of dry mouth and throat, increased heart rate, pupil dilation, urinary retention, constipation, and, at high doses, hallucinations or delirium.

What are contraindications for diphenhydramine?

Who should not take DIPHENHYDRAMINE HCL?

  • overactive thyroid gland.
  • increased pressure in the eye.
  • closed angle glaucoma.
  • high blood pressure.
  • stenosing peptic ulcer.
  • blockage of the urinary bladder.
  • enlarged prostate.
  • an inability to completely empty the bladder.

What are the metabolites of diphenhydramine?

Diphenhydramine is clinically used as antihistaminic, antitussive and sedative–hypnotic drug. The main metabolites are demethyl, bis-demethyl diphenhydramine and diphenylmethoxyacetic acid (DPMA).

Which antihistamine is least anticholinergic?

Second-generation antihistamines (eg, cetirizine, loratadine), considered nonsedating because of their relative lack of CNS penetration, are commonly prescribed to children and adults for allergic conditions. Second-generation antihistamines display no significant anticholinergic pharmacologic actions.

Is diphenhydramine citrate the same as diphenhydramine HCL?

The difference between diphenhydramine hydrochloride and diphenhydramine citrate is that the salt used to bind the diphenhydramine, is different. For diphenhydramine hydrochloride the salt is hydrochloride and for diphenhydramine citrate the salt is citrate.

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