What is sprue-like syndrome?
Sprue-like enteropathy involves unexpected weight loss and severe diarrhea that can result in chronic gastrointestinal (G.I.) tract conditions including villous atrophy that can restrict the absorption of nutrients from consumed food.
What is an enteropathy?
Enteropathy refers to any pathology of the intestine. Although enteritis specifically refers to an inflammation of the intestine, and is thus a more specific term than “enteropathy”, the two phrases are sometimes used interchangeably.
Can losartan cause sprue-like enteropathy?
Losartan is an angiotensin II receptor blocker (ARB) which may cause severe sprue-like enteropathy (SLE) with skin manifestation. Clinicians should be informed of this side effect and its reversibility after cessation of the drug.
How do you treat sprue?
Treatment for Tropical Sprue includes the use of folic acid, cobalamin, and antibiotics such as tetracycline, oxytetracycline, or ampicillin. The dosage of these medications depends on the severity of the disorder as well as how the patient responds to the therapy.
How do you cure sprue?
Tropical sprue is treated with antibiotics. This kills the bacteria overgrowth that results in this condition. Antibiotics may be given for a period of two weeks or one year. Tetracycline is the most commonly used antibiotic for treating tropical sprue.
What are symptoms of autoimmune enteropathy?
Symptoms
- Diarrhea / loose watery stools all the time.
- Poor weight gain and weight loss.
- Decreased urine output.
- Frequent infections.
- Occasional blood in the stool.
- Skin rash.
What causes enteropathy?
Causes of PLE PLE has been linked to more than 60 diseases and disorders, including congenital heart disease, cancers, immune disorders, inflammation of the gastrointestinal tract and all intestinal and digestive diseases.
Does losartan effect bowel movements?
P781 – An Unusual Cause of Diarrhea: Losartan-Induced Sprue-Like Enteropathy. Losartan is a commonly prescribed anti-hypertensive. Severe, chronic diarrhea with substantial weight loss can occur after long term Losartan use.
Can losartan cause gastrointestinal problems?
Gastrointestinal disorders: Abdominal pain, constipation, nausea, vomiting. Skin and subcutaneous tissue disorders: Urticaria, pruritus, rash, photosensitivity.
How do you treat protein loss enteropathy?
If you have PLE, your symptoms may be resolved by embolization of the abnormal communications between your liver lymphatics and intestine. The embolization is performed by injecting surgical glue diluted with x-ray visible contrast agents through a very small needle that’s inserted in your liver lymphatic vessels.
What is sprue-like enteropathy?
Sprue-like enteropathy involves unexpected weight loss and severe diarrhea that can result in chronic gastrointestinal (G.I.) tract conditions including villous atrophy that can restrict the absorption of nutrients from consumed food.
What are the symptoms of olmesartan-induced enteropathy?
Symptoms of sprue-like enteropathy include severe, chronic diarrhea with substantial weight loss, as well as abdominal pain, fatigue, bloating, nausea, vomiting, and anemia. Olmesartan-induced enteropathy can develop months to years after the initiation of therapy and, in severe cases, can lead to hospitalization.
What happens if sprue-like enteropathy goes untreated?
Without treatment, sprue-like enteropathy can lead to serious complications that include: Malnutrition – Malnourishment can be caused by damage to the small intestine they can no longer absorb much-needed nutrients. Extensive malnutrition often results in weight loss and anemia.
Can high blood pressure cause sprue-like enteropathy?
Nearly all individuals developing symptoms associated with sprue-like enteropathy have been taking high blood pressure medications to keep their blood pressure under control to improve their overall health. The most common symptoms associated with sprue-like enteropathy include: