What is elk transcription factor?

The ternary complex factor (TCF) Elk-1 is a transcription factor that regulates immediate early gene (IEG) expression via the serum response element (SRE) DNA consensus site.

What is transcription factor analysis?

Transcription Factor Enrichment Analysis (TFEA) is a robust and reliable computational method that detects positional motif enrichment associated with changes in transcription observed in response to a perturbation.

Is Gal 4 a transcription factor?

The Gal4 transcription factor is a positive regulator of gene expression of galactose-induced genes. This protein represents a large fungal family of transcription factors, Gal4 family, which includes over 50 members in the yeast Saccharomyces cerevisiae e.g. Oaf1, Pip2, Pdr1, Pdr3, Leu3.

Is TF elk a protein?

ETS Like-1 protein Elk-1 is a protein that in humans is encoded by the ELK1. Elk-1 functions as a transcription activator. It is classified as a ternary complex factor (TCF), a subclass of the ETS family, which is characterized by a common protein domain that regulates DNA binding to target sequences.

How many domains does GAL4?

GAL4 has two domains whose activities can be separated: the DNA-Binding domain and the transcriptional Activation Domain.

What are the four letters most commonly used to represent the transcription factors used in cell reprogramming or used to create induced pluripotent stem cells )?

Introduction of four transcription factors, Oct3/4, Sox2, Klf4, and c-Myc, can successfully reprogram somatic cells into embryonic stem (ES)-like cells.

How do you predict transcription factor binding sites?

Prediction of transcription factor binding sites is generally performed by scanning a DNA sequence of interest with a position weight matrix (PWM) for a transcription factor of interest [6, 7] and various pattern-matching tools have been developed for this purpose.

How much protein does elk meat have?

According to the USDA, elk has only 7 grams of fat and 18 grams of protein in a 3-ounce serving. That’s comparable to bison but higher in protein and lower in fat than most beef. Studies show that elk is also high in iron and B vitamins.

Are ELK3 and elk3d different proteins with different subcellular localizations?

In summary, we provide evidence of Elk3 and Elk3d protein expression in brain and heart, and have shown that the two proteins appear to have different subcellular localizations. Elk3d protein does not form complexes with DNA containing an ETS binding site

Is elk3d an ERK substrate?

ERK substrates can be localized to the nucleus or cytoplasm (Yoon and Seger, 2006), and Elk3d protein is a putative substrate for ERK viathe FXFP motif, which can function independently of the domain D docking site for MAP kinases (Fantz et al., 2001; Jacobs et al., 1999; Zhang et al., 2008) that is not present in Elk3d (Fig. 3).

Where are elk mRNAs expressed in the adult dorsal root ganglia?

We show by RT-PCR that the previously described Elk1, Elk3/Elk3b/Elk3c and Elk4 mRNAs are expressed in adult dorsal root ganglia (DRG), together with the novel alternatively spliced isoforms Elk1b, Elk3d and Elk4c/Elk4d/Elk4e. These isoforms are also expressed in brain, heart, kidney and testis.

Is Elk-1 downstream of ERK?

The transcription factor Elk-1 is downstream of ERK, and its activity, regulated by ERK-dependent phosphorylation, leads to transcriptional activation of target genes ( Davis, Vanhoutte, Pagès, Caboche, & Laroche, 2000 ).