What is Plummer-Vinson syndrome associated with?

What is Plummer-Vinson syndrome associated with?

Plummer-Vinson syndrome is a condition that can occur in people with long-term (chronic) iron deficiency anemia. People with this condition have problems swallowing due to small, thin growths of tissue that partially block the upper food pipe (esophagus).

How common is Plummer-Vinson syndrome?

In the first half of the 20th century Plummer-Vinson syndrome seemed to be common in Caucasians of Northern countries, particularly among middle-aged women [8]. Nowadays, it is extremely rare.

What Mees line?

Mees’ lines (also known as Aldrich or Reynolds’ lines) are transverse white bands on the nail plate laid down during periods of stress. Common associations are poisioning (arsenic, thallium, fluorosis), severe infection, renal disease, cardiac failure, and malignant disease.

What is Onychorrhexis of the nail?

Onychorrhexis is a condition where vertical ridges form in your nails. This can be caused by several conditions.

What is Plummer-Vinson syndrome and how is it treated?

Plummer-Vinson syndrome is a rare condition most often diagnosed in middle-aged women. Also known as Paterson-Brown Kelly syndrome, it was first described in 1919 by doctors in Philadelphia. Scientists noted a large number of cases in Sweden in the early twentieth century before food there was routinely fortified with iron.

What are the signs and symptoms of Plummer-Vinson syndrome?

Plummer-Vinson syndrome classically presents as a triad of iron-deficiency anemia, postcricoid dysphagia, and upper esophageal webs.[2]  Long-standing iron deficiency anemia can present as dyspnea or difficulty breathing, tachycardia, weakness, pallor, and koilonychia or spoon nails.

What is the prevalence of Plummer-Vinson syndrome?

[1]Plummer Vinson syndrome is more common in middle-aged women who appear to be at an increased risk of developing squamous cell carcinoma of the pharynx and proximal esophagus.[2]

What is Plummer-Vinson or Paterson-Kelly syndrome?

Plummer-Vinson or Paterson-Kelly syndrome presents as a classical triad of dysphagia, iron-deficiency anemia and esophageal webs. Exact data about the epidemiology of the syndrome are not available; the syndrome is extremely rare.