Are B cells stored in lymph nodes?
A simplified drawing of a human lymph node. B cells are primarily clustered in structures called lymphoid follicles, whereas T cells are found mainly in the paracortex. Both types of lymphocytes are attracted by chemokines to enter the lymph node from (more…)
What are the two main types of lymphocytes quizlet?
There are two main types lymphocytes: T cells and B cells.
How do B lymphocytes produce antibodies?
Antibodies are produced by specialized white blood cells called B lymphocytes (or B cells). When an antigen binds to the B-cell surface, it stimulates the B cell to divide and mature into a group of identical cells called a clone. Antibodies attack antigens by binding to them.
Where do B lymphocytes mature quizlet?
B cells mature in specialized bone marrow sites, & T cells mature in the thymus gland.
How do B cells enter lymph nodes?
T cells enter the lymph nodes through high endothelial venules, and move around within the T-cell area, transiently interacting with large numbers of dendritic cells. B cells enter by the same route and migrate through the T-cell area to the follicles, before finally leaving the node and re-entering the circulation.
Where do B lymphocytes mature?
the bone marrow
Where do B cells mature? B cells both originate from and mature in the bone marrow, which is the soft fatty tissue inside bones.
What do B lymphocytes mature into?
A long-lived, non-proliferating antibody-secreting cell arising from B cell differentiation. There is evidence that B cells first differentiate into a plasmablast-like cell, then differentiate into a plasma cell.
How do B cells differentiate?
activated B cells differentiate into plasma cells in primary foci that are outside of the follicles, then migrate to the medullary cords of the lymph node or to the bone marrow. Secrete IgM within 4 days. Other activated B cells enter the follicle, divide and differentiate; germinal centers form.
What is the function of B lymphocytes?
The B lymphocyte (B cell) is one of the most important cells of the body. These cells form part of the adaptive immune response by producing antibodies and presenting antigens to T cells.
What is the difference between B and T lymphocytes?
B and T lymphocytes arise from common lymphoid progenitor cells within the bone marrow. The progenitor cells that are committed to the B cell lineage are selected at random. T cell progenitors migrate to the thymus for maturation whereas B cell progenitors remain in the bone marrow.
How do B cells differentiate into memory B cells?
Some B lymphocytes will differentiate into memory B cells, which are are long-lived cells that remain within the body and allow a more rapid response to future infections. If the host is re-exposed to the same antigen, these cells rapidly proliferate with assistance from T cells.
How do B lymphocytes differentiate into plasma cells?
Once activated, B lymphocytes can differentiate into plasma cells. Plasma cells are large cells with abundant endoplasmic reticulum, which allows them to produce large quantities of antibodies against specific antigens. They respond to signals from T cells during infection and continue to produce antibodies until the infection is controlled.