Does oseltamivir need renal adjustment?
Renal Dosing Dose adjustment is recommended for adult patients with creatinine clearance between 10 and 60 mL/min and patients with end-stage renal disease (ESRD) undergoing hemodialysis or continuous peritoneal dialysis receiving TAMIFLU for the treatment of influenza.
What is the therapeutic class of oseltamivir?
Oseltamivir is in a class of medications called neuraminidase inhibitors. It works by stopping the spread of the flu virus in the body.
What is oseltamivir 6 mg/mL suspension?
Oseltamivir is used to treat symptoms caused by the flu virus (influenza). It helps make the symptoms (such as stuffy nose, cough, sore throat, fever/chills, aches, tiredness) less severe and shortens the recovery time by 1-2 days.
How is oseltamivir phosphate administered?
The recommended dosage of TAMIFLU for prophylaxis of influenza in adults and adolescents 13 years and older is 75 mg orally once daily (one 75 mg capsule or 12.5 mL of oral suspension once daily) for at least 10 days following close contact with an infected individual and up to 6 weeks during a community outbreak.
How close together can you take Tamiflu doses?
Adults and teenagers—75 milligrams (mg) or 12.5 milliliters (mL) two times a day (one in the morning and one in the evening) for 5 days. Children 1 year of age and older—Dose is based on body weight and must be determined by your doctor. It is usually between 30 to 75 mg or 5 to 12.5 mL two times a day for 5 days.
How do you take oseltamivir phosphate 75 mg?
Swallow the capsules whole with water. Do not break or chew the capsules. Tamiflu can be taken with or without food, although taking it with food can reduce the chance of feeling or being sick (nausea or vomiting). People who find it hard to take capsules can use a liquid medicine, Tamiflu oral suspension.
How far apart should you take Tamiflu?
To treat flu symptoms: Take Tamiflu every 12 hours for 5 days. To prevent flu symptoms: Take Tamiflu every 24 hours for 10 days or as prescribed.
What is oseltamivir 75mg?
How many hours apart should you take Tamiflu?
How much oseltamivir should I take for kidney infection?
The recommended dose in adults with normal renal function is 75 mg twice a day for 5 days for curative treatment and 75 mg once a day for preventive treatment. Oseltamivir is extensively converted by hepatic esterases to its active metabolite, oseltamivir carboxylate.
How much oseltamivir should be taken to reduce CrCl levels?
For patients with CrCl between 15 and 30 ml/min (stage 4), a dosage reduction of 50% (75 mg once daily in curative treatment and 75 mg every other day in prophylactic treatment) is recommended [ 5 ]. There are no data on the pharmacokinetics and/or the tolerance of oseltamivir in patients with CrCl <15 ml/min and in patients on dialysis.
What are the pharmacokinetics of oseltamivir in patients with renal failure?
Indeed, the pharmacokinetics of oseltamivir are modified in patients with renal failure. The clearance of the parent compound and its metabolite decrease proportionally with the reduction of creatinine clearance (CrCl).
How often should I take oseltamivir for H5N1?
Oseltamivir. The evidence of the effectiveness of oseltamivir for prophylaxis of H5N1 infection is based on the results of trials on the prevention of ordinary influenza. The recommended dose in adults with normal renal function is 75 mg twice a day for 5 days for curative treatment and 75 mg once a day for preventive treatment.