How do African Americans treat hypertension?
Instead of ACE inhibitors or ARBs, experts recommend Black adults start with either a thiazide diuretic, such as chlorthalidone or hydrochlorothiazide, or a calcium channel blocker (CCB) like amlodipine (Norvasc).
Why are ACEI and ARBs not recommended for African black population?
It is commonly reported that the blood pressure lowering efficacy of renin angiotensin system (RAS) inhibitors is attenuated in African Americans due to a greater likelihood of having a low renin profile. Therefore these agents are often not recommended as initial therapy in African Americans with hypertension.
Which antihypertensive medication is more effective in African American?
Black Patients Respond Preferentially to Diuretics In the ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial) in the United States, in which 40% of participants were black, diuretic was the most successful drug class.
What is black hypertension?
Blacks are found to develop hypertension at an earlier age than whites. An assessment of US children aged 8–17 years found systolic blood pressures to be 2.9 mmHg and 1.6 mmHg higher in black boys and girls compared with age-matched white boys and girls.
Are beta blockers good for African American?
It has been reported that beta blockers are not effective antihypertensives in black populations. A review of the literature revealed that, for the most part, studies drawing this conclusion were of small sample size, lacked controls, and did not represent the demographics of the US black population.
Is lisinopril a beta blocker or ACE inhibitor?
Lisinopril belongs to a class of medications called ACE inhibitors. ACE is short for angiotensin-converting enzymes. Lisinopril is considered an antihypertensive drug. In general, antihypertensive drugs are used as a treatment for high blood pressure.
Is lisinopril a ACE inhibitor?
About lisinopril Lisinopril belongs to a class of medicines called angiotensin-converting enzyme inhibitors, or ACE inhibitors. It is prescribed for a number of different reasons.
Why is amlodipine given to African American?
Calcium blockers are with diuretics among the most effective classes of drugs to reduce blood pressure in patients of African ancestry [3,7]. This drug type remains effective in all subgroups of sex, age and blood pressure strata, including high baseline diastolic blood pressure (>/= 110 mm Hg).
Why can’t African Americans use ACE inhibitors?
Angiotensin converting enzyme (ACE) inhibitors have been avoided as an initial therapeutic option in the treatment of hypertension in African-Americans. A major reason for this has been the widespread perception of clinicians that these agents have poor blood pressure (BP) lowering efficacy in this population.
Why can’t African Americans take beta blockers?
Beta-blockers are generally less effective in Black hypertensives26 as a result of the tendency towards a low-renin state and a lower cardiac output, with increased peripheral resistance.
Is lisinopril safe for African American?
However, lisinopril was associated with an increased risk for heart failure (relative risk [RR] for African Americans=1.32; 95% CI, 1.11–1.58) and stroke (RR for African Americans=1.4; 95% CI, 1.17–1.68), and amlodipine was associated with a higher risk of heart failure (RR in African Americans=1.47; 95% CI, 1.24–1.74) …
What are the 4 worst blood pressure drugs?
Lisinopril.
What are the worst blood pressure medicines?
5 Worst Blood Pressure Medications for Men. The most common drugs for high blood pressure, or hypertension, today are the ACE inhibitors. These include enalapril (Vasotec), lisinopril (Prinivil, Zestril) and ramipril (Altace).
What is hypertension management?
The goal of hypertension treatment is to lower high blood pressure and protect important organs, like the brain, heart, and kidneys from damage. Treatment for hypertension has been associated with reductions in stroke (reduced an average of 35%-40%), heart attack (20%-25%), and heart failure (more than 50%), according to research.