What is eculizumab injection?
Eculizumab injection is used to treat a type of blood disease called paroxysmal nocturnal hemoglobinuria (PNH). This medicine helps reduce red blood cell destruction or breakdown (hemolysis) in patients with PNH.
What disease does Soliris treat?
Generic Name: eculizumab This medication is used to treat a certain blood disorder (paroxysmal nocturnal hemoglobinuria). This disorder can cause a decrease in red blood cells (anemia).
How does Soliris work for myasthenia gravis?
Soliris is designed to block part of the immune system called the terminal complement cascade, consisting of a series of reactions that trigger the damaging immune response seen in myasthenia gravis. Soliris binds to and inhibits the cleavage of a protein called C5, an essential step at the start of the cascade.
Is eculizumab a chemo drug?
Eculizumab is the generic name for the trade chemotherapy drug Soliris. In some cases, health care professionals may use the trade name Soliris when referring to the generic drug name eculizumab.
How long is Soliris treatment?
Soliris therapy is given through intravenous infusion and the procedure usually lasts for about 35 minutes in adults and about one to four hours in infants. Adults usually receive Soliris weekly for five weeks and then once every two weeks until symptoms improve.
What is aHUS disease?
Atypical hemolytic-uremic syndrome is a disease that primarily affects kidney function. This condition, which can occur at any age, causes abnormal blood clots (thrombi) to form in small blood vessels in the kidneys. These clots can cause serious medical problems if they restrict or block blood flow.
Is soliris an immunosuppressant?
SOLIRIS® (Eculizumab) Immunosuppressant.
How much is Soliris cost?
Priced at $678,392 per year, Soliris is used to treat paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome — blood disorders that result in the destruction of red blood cells. The dosing regimen for Soliris can differ depending on the age of the patient and the condition being treated.
What are the side effects of eculizumab?
COMMON side effects
- throat irritation.
- a common cold.
- inflammation of the tissue lining the sinuses.
- constipation.
- urinary tract infection.
- backache.
- muscle pain.
- fever.
Are Soliris safe?
Soliris affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor right away if you have a headache and fever with nausea or vomiting, skin rash, body aches, flu symptoms, confusion, sensitivity to light, or stiffness in your neck or back.
How much does Soliris cost?
What are the side effects of Soliris?
What are the side effects of Eculizumab (Soliris)?
- fever and a headache or skin rash;
- headache with nausea and vomiting;
- body aches, flu symptoms;
- confusion, increased sensitivity to light; or.
- stiffness in your neck or back.