What is NUCALA used to treat?
NUCALA is an add-on, prescription maintenance treatment for patients 6 and older with severe eosinophilic asthma. NUCALA is not used to treat sudden breathing problems. *For ages 12 and older.
What is Mepolizumab used for?
Mepolizumab injection is used along with other medications to prevent wheezing, difficulty breathing, chest tightness, and coughing caused by asthma in certain children 6 years of age and older and adults whose asthma is not controlled with their current asthma medication(s).
How do you reconstitute NUCALA?
Reconstitute NUCALA in the vial with 1.2 mL Sterile Water for Injection, USP, preferably using a 2- or 3-mL syringe and a 21-G needle. The reconstituted solution will contain a concentration of 100 mg/mL mepolizumab. Do not mix with other medications.
What is NUCALA Autoinjector?
The NUCALA Autoinjector is a monthly injection for severe eosinophilic asthma patients ages 12 and older. Together, you and your doctor can decide if at-home administration with NUCALA is right for you.
Which injection is used for asthma?
The main injections for asthma are: benralizumab (Fasenra) omalizumab (Xolair) mepolizumab (Nucala)
Does NUCALA lower immune system?
Increased infections (infections related to alteration in immune response) Nucala lowers the body’s levels of certain white blood cells, called eosinophils, and patients with low white blood cell counts have a higher chance of developing an infection.
How is NUCALA administered?
You will receive NUCALA for EGPA as 3 separate 100-mg injections given at the same time in an office visit or at home every 4 weeks. You, your caregiver, or your doctor will inject NUCALA just under your skin (subcutaneously) into your thigh or abdomen. Your caregiver or your doctor may also inject in your upper arm.
Is NUCALA safe?
NUCALA can cause serious side effects, including: Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction: swelling of your face, mouth, and tongue. breathing problems. fainting, dizziness, feeling light-headed (low blood pressure)
Can NUCALA be self administered?
Nucala injection is intended for use under the guidance of a healthcare provider. A patient may self-inject or the patient caregiver may administer Nucala injection subcutaneously after the healthcare provider determines it is appropriate.
How do I give NUCALA?
How often is Mepolizumab given?
The recommended dosage of NUCALA in adults and adolescents aged 12 years and older is 100 mg administered once every 4 weeks by subcutaneous injection into the upper arm, thigh, or abdomen [see Dosage and Administration (2.5, 2.6)].
What is the indication of Nucala?
Nucala is indicated for the treatment of adult and pediatric patients aged 12 years and older with hypereosinophilic syndrome (HES) for ≥6 months without an identifiable non-hematologic secondary cause. Nucala is for subcutaneous use only.
How is Nucala used to treat EGPA?
Nucala is indicated for the treatment of adult patients with eosinophilic granulomatosis with polyangiitis (EGPA). Nucala is for subcutaneous (SC) use only. The recommended dosage of Nucala in adults and adolescents aged 12 years and older is 100 mg administered once every 4 weeks by SC injection into the upper arm, thigh, or abdomen.
What is the recommended dosage of Nucala?
The recommended dosage of NUCALA is 300 mg administered once every 4 weeks by SC injection as 3 separate 100-mg injections into the upper arm, thigh, or abdomen. It is recommended that the individual 100-mg injections be administered at least 5 cm (approximately 2 inches) apart if more than 1 injection is administered at the same site.
What is the concentration of Nucala in a syringe?
Nucala is supplied as a sterile, white to off-white, preservative-free, lyophilized powder for SC injection after reconstitution. Upon reconstitution with 1.2 mL of Sterile Water for Injection, USP [see Dosage and Administration (2.3)], the resulting concentration is 100 mg/mL and delivers 1 mL.