Is ibuprofen an organic compound?

Is ibuprofen an organic compound?

Structure for FDB022743 (Ibuprofen) Belongs to the class of organic compounds known as phenylpropanoic acids. Phenylpropanoic acids are compounds with a structure containing a benzene ring conjugated to a propanoic acid.

What is the chemistry behind ibuprofen?

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin.

Is ibuprofen an aromatic?

Ibuprofen ((RS)-2-(4-(2-methylpropyl)phenyl)propanoic acid) consists of an aromatic ring bridging an isobutyl and a propanoic acid group (see Fig. 1) so that a rich conformational landscape can be expected.

Is ibuprofen natural or synthetic?

Abstract. The synthesis of ibuprofen was accomplished from isobutylbenzene. The synthetic process included a Friedel-Crafts acylation, reduction, chloride substitution, and Grignard reaction.

Is ibuprofen an element or compound?

(RS)-2-(4-(2-methylpropyl)phenyl)propanoic acid
Ibuprofen/IUPAC ID

What is a contraindication for ibuprofen?

You shouldn’t take ibuprofen if you: have a history of a strong, unpleasant reaction (hypersensitivity) to aspirin or other NSAIDs. have a current or recent stomach ulcer, or you have had one in the past. have severe heart failure.

What are the indications of ibuprofen?

IBUPROFEN INDICATIONS Like other OTC pain relievers, ibuprofen temporarily relieves minor aches and pains due to headache, backache, the common cold, minor pain of arthritis, toothache, menstrual cramps, and muscular aches, and temporarily reduces fever.

What are the contraindications of ibuprofen?

Ibuprofen is contraindicated for use in patients with:

• known hypersensitivity or idiosyncratic reaction to ibuprofen (or any of the other ingredients in the product)
• known hypersensitivity to aspirin and other NSAIDs.
• asthma that is aspirin or NSAID sensitive.
• active gastrointestinal bleeding or peptic ulceration.

Is ibuprofen patented?

A patent for ibuprofen was granted to Boots in 1962 and it was approved as a prescription drug seven years later. According to Dave McMillan, former head of healthcare development at Boots UK, ibuprofen was an extremely important drug to the company.

What is the chemical name of ibuprofen?

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2- (4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin.

Is ibuprofen a propionic acid?

It derives from a propionic acid. It is a conjugate acid of an ibuprofen (1-). Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics.

What is the mechanism of action of ibuprofen?

Create. 2004-09-16. Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes.

What is the pKa of ibuprofen in organic chemistry?

The pKa of ibuprofen is 4.91 (4), indicating that this compound will primarily exist in the dissociated form in the environment and anions generally do not adsorb to organic carbon and clay more strongly than their neutral counterparts (5).