Can an overdose cause tachycardia?
Verapamil or diltiazem toxicity usually patients present with sinus bradycardia, on the hand dihydropyridine overdoses cause peripheral vasodilatation causing reflex tachycardia [55].
What is the treatment after acute overdose agents used in addition to fab?
Therapeutic options range from simply discontinuing digoxin therapy for stable patients with chronic toxicity to digoxin Fab fragments, cardiac pacing, antiarrhythmic drugs, magnesium, and hemodialysis for severe acute toxicity.
What can be used to neutralize poison?
Try to neutralize the poison with lemon juice or vinegar, or any other substance, unless you are told to do so by the Poison Control Center or a doctor. Use any “cure-all” type antidote. Wait for symptoms to develop if you suspect that someone has been poisoned.
What is the antidote for digitalis overdose?
In the case of severe digoxin intoxication, an antidote digoxin immune Fab (Digibind) is available.
What is urine alkalinization?
Urine alkalinization is a treatment regimen that increases poison elimination by the administration of intravenous sodium bicarbonate to produce urine with a pH > or = 7.5. Experimental and clinical studies confirm that urinary alkalinization increases salicylate elimination, although the mechani …
Does urinary alkalinization increase salicylate elimination?
Experimental and clinical studies confirm that urinary alkalinization increases salicylate elimination, although the mechani … Urine alkalinization is a treatment regimen that increases poison elimination by the administration of intravenous sodium bicarbonate to produce urine with a pH > or = 7.5.
Is alkalinization of the urine effective for drug-induced rhabdomyolysis?
Alkalinization of the urine is a controversial treatment of drug-induced rhabdomyolysis and has proven to be beneficial in some patients. Summary. A high index of suspicion, early recognition, and adequate treatment will result in an excellent prognosis of drug-induced rhabdomyolysis.
How do you alkalize urine in a diuretic?
Administer lactated Ringer or isotonic sodium chloride solution for volume expansion at 10-20 mL/kg/h until a 1- to 1.5-mL/kg/h urine flow is established. Provide maintenance fluids to maintain urinary alkalization. Forced diuresis is not recommended. The greater the urine flow, the more difficult it is to alkalinize the urine.