Does the American Heart Association recommend statins?
The following are guideline recommendations for statin treatment: Patients ages 20-75 years and LDL-C ≥190 mg/dl, use high-intensity statin without risk assessment. T2DM and age 40-75 years, use moderate-intensity statin and risk estimate to consider high-intensity statins.
When is a statin contraindicated?
Statins are contraindicated for use by patients with active hepatic disease or unexplained persistent elevations in aminotransferase levels. Statins are contraindicated during pregnancy and while breastfeeding because of the effects on the cholesterol pathway.
What is the indication for statins?
Indications of statin in clinical practice. Statins are indicated as an adjunct to diet to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B and triglycerides; and to increase HDL cholesterol in patients with: Primary hypercholesterolaemia. Mixed dyslipidemia.
Is aspirin better than statins?
Although the absolute risk for bleeding appears low with aspirin, so does the absolute benefit: on average a reduction of 0.1% (number needed to treat of 1000). On the other hand, statins offer a stronger degree of benefit (absolute reduction on the order of 1% to 2%, number needed to treat 50-100).
What is the safest statin drug?
Simvastatin and pravastatin had the best safety profile, according to this review. Overall, the researchers found a 9 percent increased risk of type 2 diabetes in people taking statins.
Can I refuse statins?
We know that for patients at high risk, statins can do this — and potentially save lives. Before you refuse to take a statin or stop taking a statin, consult your doctor. He or she can explain why you may benefit from the drug or help you find a different statin if you experience side effects.
Is biostatistics a good profession?
Biostatistician is becoming a great career choice for those who are interested in medicine but don’t want to become health care providers. This career offers professional variety, as there are a number of topics to research in biology and medicine.
What are the career options in biostatistics?
What is the purpose of Biostatistics?
Biostatistics is used to determine how diseases develop, progress and spread. For example, biostatisticians use statistics to predict the behavior of an illness like the flu. It’s used to help predict the mortality rate, the symptoms and even the time of year people might get it [source: CSIRO].
What does biostatistics mean to US?
What does biostatistics mean to us. One definition of biostatistics could be precisely this, the rigorous and objective conversion of medical and/or biological observations into knowledge. Both consumers of biostatistical principles and biostatisticians themselves vary in the extent to which they recognize the need to continue the improvement.