How do you stage mycosis fungoides?
Mycosis fungoides may go through the following phases:
- Premycotic phase: A scaly, red rash in areas of the body that usually are not exposed to the sun.
- Patch phase: Thin, reddened, eczema-like rash.
- Plaque phase: Small raised bumps (papules) or hardened lesions on the skin, which may be reddened.
What is early stage mycosis fungoides?
STAGE I: The first sign of mycosis fungoides is usually generalized itching (pruritus), and pain in the affected area of the skin. Sleeplessness (insomnia) may also occur. Red (erythematous) patches scattered over the skin of the trunk and the extremities appear.
What is mycosis fungoides patch stage?
The patch stage of mycosis fungoides is characterized by usually erythematous macules that may have a fine scale, may be single or multiple, and may be pruritic (see the image below). In dark-skinned individuals, the patches may appear as hypopigmented or hyperpigmented areas.
Can mycosis fungoides be a secondary cancer?
Mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL), has an incidence of 6.4 per million people . Patients with CTCL have an increased risk of the development of secondary malignancies, particularly lymphomas [2 ,3].
Who is at risk for mycosis fungoides?
Mycosis fungoides can affect anyone but is most common in adults over 50. Men are twice as likely as women to develop mycosis fungoides.
Does mycosis fungoides always itch?
Plaque stage of mycosis fungoides As the cancer spreads, raised and often itchy patches of thicker skin appear.
What are the stages of Stage 2 mycosis fungoides?
Stage II Mycosis Fungoides. Stage II is divided into stages IIA and IIB as follows: Stage IIA: Patches, papules, and/or plaques cover any amount of skin surface. Lymph nodes are abnormal, but they are not cancerous. Stage IIB: One or more tumors that are 1 centimeter or larger are found on the skin.
What is metastatic mycosis fungoides?
The metastatic tumor is the same type of cancer as the primary tumor. For example, if mycosis fungoides spreads to the liver, the cancer cells in the liver are actually mycosis fungoides cells. The disease is metastatic mycosis fungoides, not liver cancer. Stage IA: Patches, papules, and/or plaques cover less than 10% of the skin surface.
How is mycosis fungoides diagnosed from a skin biopsy?
A definitive diagnosis from a skin biopsy requires the presence of mycosis fungoides and Sézary syndrome cells (convoluted lymphocytes), a band-like upper dermal infiltrate, and epidermal infiltrations with Pautrier abscesses (collections of neoplastic lymphocytes).
What is the AJCC classification for mycosis fungoides?
The American Joint Committee on Cancer (AJCC) has designated staging by TNM (tumor, node, metastasis) classification to define mycosis fungoides. [ 1] Peripheral blood involvement with mycosis fungoides or Sézary syndrome cells is correlated with more advanced skin stage, lymph node and visceral involvement, and shortened survival.