How is amiodarone-induced hyperthyroidism treated?

How is amiodarone-induced hyperthyroidism treated?

Amiodarone-induced thyrotoxicosis

1. If possible, withdraw amiodarone.
2. Carbimazole (or methimazole), 30–60 mg/day.
3. Definitive treatment after restoration of euthyroidism is either by radioiodine or thyroidectomy.

What are the management options for amiodarone-induced hypothyroidism?

Amiodarone-induced hypothyroidism AIH may be managed by either discontinuation of amiodarone therapy or thyroid hormone replacement. Discontinuation of amiodarone may not be feasible because of the underlying indication for its use, especially in the treatment of difficult ventricular tachyarrhythmias.

How is drug induced hyperthyroidism treated?

The drugs used to treat hyperthyroidism or are related to thyroid function that can result in drug-induced hypothyroidism are propylthiouracil, radioactive iodine, potassium iodide, and methimazole. Iodides, in general, alter thyroid function.

Is amiodarone contraindicated in hyperthyroidism?

Amiodarone inhibits entry of T4 and T3 into the peripheral tissue. Serum T4 levels increase by an average of 40% above pretreatment levels after 1-4 months of treatment with amiodarone. This, in itself, does not constitute evidence of hyperthyroidism (thyrotoxicosis).

Why amiodarone causes hypothyroidism and hyperthyroidism?

However, amiodarone is associated with a number of side effects, including thyroid dysfunction (both hypo- and hyperthyroidism), which is due to amiodarone’s high iodine content and its direct toxic effect on the thyroid.

Does amiodarone cause hyperthyroidism?

What is the best medication for hyperthyroidism?

Treatment options for hyperthyroidism include:

• Antithyroid drugs methimazole (Tapazole) or propylthiouracil (PTU): These drugs block the ability of your thyroid to make hormones.
• Radioactive iodine: Radioactive iodine is an oral medication that your overactive thyroid cells absorb.

Why does amiodarone induce hyperthyroidism?

How do you administer amiodarone injection?

Add 3 mL of Amiodarone HCl Injection (150 mg) to 100 mL D5W (concentration = 1.5 mg/mL). Infuse 100 mL over 10 minutes. Followed by Slow: 360 mg over the NEXT 6 hours (1 mg/min).