What does it mean when you are HBsAg positive and HBeAg positive?

What does it mean when you are HBsAg positive and HBeAg positive?

Serum levels of both HBeAg and HBsAg rise rapidly during the period of viral replication. The presence of HBeAg in serum correlates with hepatitis B virus (HBV) infectivity, the number of infectious virions, and the presence of HBV core antigen in the infected hepatocytes.

What does HBeAg reactive mean?

A positive (reactive) HBeAg result combined with a negative (non-reactive) anti-HBe result confirms a high degree of contagiousness. When the anti-HBe is also reactive, this means the individual is in the process of healing and is less contagious.

What does reactive HBsAg mean?

■ HBsAg (hepatitis B surface antigen): when this is “positive” or “reactive,” it means the person is currently infected with hepatitis B and is able to pass the infection on to others.

What is if HBeAg positive?

What HBeAg Test Results Mean. A positive test for the hepatitis B e-antigen means that there is an active infection with the hepatitis B virus and the virus is actively multiplying. Anyone who is in contact with your blood without protection may be at risk of contracting hepatitis B from you.

Is HBeAg negative good or bad?

HBeAg‐negative CHB is a potentially severe disease that rapidly progress to cirrhosis and related complications. Although treatment is available, sustained virological and biochemical response is poor after the recommended duration of treatment.

What is the normal range of HBeAg?

For example, a hepatitis B surface antigen (HBsAg) level of less than 1 s/c is considered negative, while a level of more than 5 s/c is considered positive. Any value between 1 and 5 s/c is indeterminate and should be repeated.

What is the treatment for HBeAg-negative?

The most common antiviral treatments are either entecavir (Baraclude) or tenofovir (Viread). These two are considered the most powerful at quickly reducing viral load (HBV DNA) and have a very low risk of causing drug resistance, which is critical considering the long-term treatment required by HBeAg-negative patients.

Can HBsAg positive become negative?

It can happen, especially in older adults after a long period of “inactive” hepatitis B infection. About 1 to 3 percent of people with chronic hepatitis B lose HBsAg each year, and about half of all people with chronic infections who live up to age 75 will lose HBsAg, depending on the amount of HBV DNA in their blood.

Can Hep B be cured?

Infants and children are more likely to develop a chronic (long-lasting) hepatitis B infection. A vaccine can prevent hepatitis B, but there’s no cure if you have the condition. If you’re infected, taking certain precautions can help prevent spreading the virus to others.

What does a reactive HBsAg indicate?

This tests for the presence of virus. A “positive” or “reactive” HBsAg test result means that the person is infected with the hepatitis B virus, which can be an “acute” or a “chronic” infection. Infected people can pass the virus on to others through their blood and infected bodily fluids.

What does reactive HBsAg test result indicate?

HBsAg (Hepatitis B surface antigen) – A “positive” or “reactive” HBsAg test result means that the person is infected with hepatitis B. This test can detect the actual presence of the hepatitis B virus (called the “surface antigen”) in your blood.

How can HBsAg become negative?

Therefore, HBsAg will be negative if the acute infection of hepatitis B is resolved and the hepatitis infection does not go to a chronic state. Also of course if the patient is never infected by the virus. There is a phase known as “window period” that happens shortly after the acute infection is resolved.

What does ‘HBsAg non-reactive’ mean?

Sounds okay: Anti-hbs reactive means you have recovered from hepatitis b or been immunized. Hbsag-nonreactive means you do not have the hepatitis b virus in your blood. Anti-hcv non-reactive means you have not met / are not infected by the hepatitis c virus.

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