What happens in compensated metabolic alkalosis?

What happens in compensated metabolic alkalosis?

Compensation. Compensation for metabolic alkalosis occurs mainly in the lungs, which retain carbon dioxide (CO2) through slower breathing, or hypoventilation (respiratory compensation). CO2 is then consumed toward the formation of the carbonic acid intermediate, thus decreasing pH.

How do you fix compensated metabolic alkalosis?

Metabolic alkalosis treatment uses an intravenous (IV) line to deliver fluid and other substances, such as:

  1. Saline infusion.
  2. Potassium replacement.
  3. Magnesium replacement.
  4. Chloride infusion.
  5. Hydrochloric acid infusion.
  6. Stopping the medications that caused the condition, for example high doses of diuretics.

How is ABG compensation calculated?

If the pH is not within or close to the normal ranges, then a partial-compensation exists. If the pH is back within normal ranges then a full-compensation has occurred. A non-compensated or uncompensated abnormality usually represents an acute change occurring in the body.

How do you calculate compensation for metabolic acidosis?

To review, Winter’s Formula is used to predict the PaCO2 which should result if there is appropriate respiratory compensation for a metabolic acidosis: predicted PaCO2 = 1.5 x [HCO3-] + 8.

How is compensated metabolic acidosis determined?


  1. Examine the pH level. If the pH is normal, but both PaCO2 and HCO3 are abnormal, compensation has occurred.
  2. Examine the PaCO2 level along with the HCO3 level.
  3. Interpret the results.

How do you calculate metabolic compensation for respiratory acidosis?

III. Calculation: Calculated PaCO2 in Metabolic Conditions

  1. Metabolic Acidosis with expected compensation. PaCO2 = 1.5 x HCO3 + 8 (+/- 2) PaCO2Delta = 1.2 x BicarbDelta. PaCO2 will not typically drop below 10 mmHg in respiratory compensation.
  2. Metabolic Alkalosis with expected compensation. PaCO2 = 0.7 x HCO3 + 20 (+/- 1.5)

What is acidosis alkalosis?

Acidosis is a condition in which there is too much acid in the body fluids. It is the opposite of alkalosis (a condition in which there is too much base in the body fluids).

How is compensated respiratory acidosis treated?


  1. Bronchodilator medicines and corticosteroids to reverse some types of airway obstruction.
  2. Noninvasive positive-pressure ventilation (sometimes called CPAP or BiPAP) or a breathing machine, if needed.
  3. Oxygen if the blood oxygen level is low.
  4. Treatment to stop smoking.

What is compensated ABG?

When PaCO2 and HCO3 values are high but pH is acidic, then it indicates partial compensation. It means that the compensatory mechanism tried but failed to bring the pH to normal. If pH is abnormal and if the value of either PaCO2 or HCO3 is abnormal, it indicates that the system is uncompensated.

What is fully compensated respiratory alkalosis?

Fully compensated respiratory alkalosis occurs when respiratory alkalosis is present, with pH normal but closer to alkalotic (7.4 – 7.45) and PaCO2 alkalotic (under 35 mmHg); and the metabolic system acts to correct it, marked by an HCO3 level that is out of range and acidic (under 22 mEq/L).

How does the body fix metabolic alkalosis?

Metabolic alkalosis is corrected with the aldosterone antagonist spironolactone or with other potassium-sparing diuretics (eg, amiloride, triamterene). If the cause of primary hyperaldosteronism is an adrenal adenoma or carcinoma, surgical removal of the tumor should correct the alkalosis.

How to fix metabolic acidosis?

Metabolic Acidosis. One of these jobs is to keep the right balance of acids in the body. The kidneys do this by removing acid from the body through urine. Metabolic acidosis is caused by a build-up of too many acids in the blood. This happens when your kidneys are unable to adequately remove the acid from your blood.

Which laboratory finding indicates metabolic alkalosis?

Laboratory tests that may be ordered include: Arterial blood gas analysis. Electrolytes test, such as basic metabolic panel to confirm alkalosis and show whether it is respiratory or metabolic alkalosis.

What are some of the causes of metabolic alkalosis?

The use of steroids.

  • The excess of antacids.
  • The excessive use of alkaline drugs,such as bicarbonate.
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