What is the function of ovotransferrin?
Ovotransferrin is the second major protein in egg white accounting for 12–13% of the total egg white proteins. It is an iron-binding protein consisting of 686 amino acids. Due to its ability to sequester iron which microbes need for survival, separated ovotransferrin can be used in foods to inhibit microbial growth.
Is ovotransferrin a protein?
Major conclusions: Similarly to the better known family member protein lactoferrin, ovotransferrin appears to be a multi-functional protein with a major role in avian natural immunity.
What is the function of Ovomucin?
Ovomucin maintains the viscosity and structure of egg albumin and thus plays a role in preventing the spread of microorganisms. It inhibits cholesterol uptake and attenuates hypercholesterolemia. It also exhibits macrophage-stimulating activity and thus acts as immune-modulators.
What is the function ovalbumin?
Ovalbumin is the major egg white protein synthesized in the hen’s oviduct, within the magnum tissue, and is responsible for egg white formation. It accounts for about 54% of the total proteins of egg albumen.
What is the isoelectric point of Ovotransferrin?
Otrf is a monomeric glycoprotein containing 686 amino acids, with a molecular weight of 77.9 kDa and an isoelectric point of 6.0 [9,10].
At what pH is Ovotransferrin neutral?
It has a binding log of 15 at a pH of 7 or above, meaning that the iron binding capacity of ovotransferrin rapidly decreased at a pH that is less than 6. This family is also known for their role in cell maturation by transporting essential nutrients to developing embryos.
What is the pI of ovalbumin?
5.19
The molecular weight of ovalbumin is 171,391.45 Da, and its isoelectric point (pI) is 5.19 (7). The major significance of ovalbumin does not reside in its biological function as a molecule. Ovalbumin provides a major interest for study because its structure provides a model for the structure of the inhibitory serpins.
What is the difference between albumin and ovalbumin?
albumin, a type of protein that is soluble in water and in water half saturated with a salt such as ammonium sulfate. Ovalbumin constitutes about 50 percent of the proteins of egg white; conalbumin is also a component. Seeds contain very small amounts of albumins (0.1–0.5 percent by weight). See also proteinuria.
What is the molecular weight of Ovotransferrin?
Otrf is a monomeric glycoprotein containing 686 amino acids, with a molecular weight of 77.9 kDa and an isoelectric point of 6.0 [9,10]. The avian transferrin gene is transcripted in the liver and the oviduct.
Where does albumin come from in the body?
Synthesis of albumin takes place in the liver, after which it is excreted into the bloodstream. Albumin can be found in the bloodstream, interstitial space, as well as other fluids. When found in other fluids in large concentrations, such as in ascites or urine, it is often an indication of underlying pathology.
What do albumin levels tell you?
A normal albumin range is 3.4 to 5.4 g/dL. If you have a lower albumin level, you may have malnutrition. It can also mean that you have liver disease or an inflammatory disease. Higher albumin levels may be caused by acute infections, burns, and stress from surgery or a heart attack.
What is ovotransferrin and why is it important?
Ovotransferrin is the second most abundant protein (~12-13% of the total egg protein) in egg white after ovalbumin. Ovotransferrin is a potent natural antimicrobial agent as it possesses antibacterial, antifungal, and antiviral properties and is also the major metal binding protein found in egg, which makes it an industrially important protein.
What is the function of transferrin?
Transferrins are iron binding proteins that belong to a family of glycoproteins including serotransferrin (often referred to simply as transferrin) in blood, ovotransferrin (conalbumin) in bird egg whites, lactoferrin in mammalian biological fluids, and melanotransferrin in membranes of melanocar-cinoma cells (Baker et al., 1987).
What is the stationary phase of ovotransferrin?
Ovotransferrin is further stabilized by conjugation to silica gel as a chiral stationary phase, and ovotransferrin-based stationary phases have been used for the separation of a basic compound, azelastine. Flavoprotein, the riboflavin-binding protein, in egg whites and yolks has been introduced as a chiral stationary phase for HPLC.
Is ovotransferrin positive or negative app?
Ovotransferrin is an iron-binding glycoprotein, found in egg white and chicken serum, belonging to the family of transferrin iron-binding glycoproteins. It is a negative APP in mammals, but a positive one in chickens [18]. It is a moderate APP, increasing 10- to 100-fold upon inflammatory stimulation.