Why is my CA125 going up?
Many different conditions can cause an increase in CA 125, including normal conditions, such as menstruation, and noncancerous conditions, such as uterine fibroids. Certain cancers may also cause an increased level of CA 125, including ovarian, endometrial, peritoneal and fallopian tube cancers.
How fast does CA125 increase?
The average time from serum CA125 increase to detection of a recurrent lesion by physical or imaging examination was 122 days. The correlation coefficient of serum CA125 level increase and tumor recurrence time was −0.674.
Can your CA125 levels fluctuate?
So, CA 125 values can and do fluctuate. Major treatment decisions, such as changing or discontinuing treatment, depend on multiple factors that you and your physician will consider. The trend in your CA 125 values is only one of these factors.
Can inflammation cause CA125 to rise?
As the CA 125 molecule is identified in normal peritoneal and fallopian tubes, it is not surprising that inflammation of these tissues can result in an increased concentration of serum CA 125.
What is the highest CA 125 level?
While a CA 125 level over 35 may indicate cancer, it does not always mean the person has cancer. A CA 125 level over 35 is only a potential indicator….CA 125 Levels Chart.
|CA 125 Levels (units/mL)
|Possible cancer. More tests will be needed for a diagnosis.
Can CA 125 go up during chemo?
Results: One woman was excluded due to normal CA 125 values. The remaining 19 patients displayed a significant decrease in CA 125 during the 14-day period after chemotherapy. Conclusion: In the present study, no chemotherapy-induced increase of CA 125 within the first 14 days after chemotherapy could be demonstrated.
What is a bad CA125 level?
The tumor marker Ca 125 is a prognostic factor. Levels around 100 U/l are indicative of a bad prognosis.
What is considered high CA125?
Generally speaking, the normal range of CA-125 is considered to be 0-35 units/mL, while a level above 35 units/mL is considered to be a high CA-125 level.
What is considered high CA 125?
What is the relationship between CA125 and recurrence?
The increased level of serum CA125 has a negative correlation with the time before finding the recurrent lesion. The higher and faster serum CA125 increases, the shorter the time to find the recurrent lesion by physical or imaging examination. These results are similar to the results of Levy .
Is ca 125 a reliable test?
My CA 125 has been a reliable test since surgery this past March. On Thursday, I had my 3 month blood tests and the CA 125 went from 8 to 15. I know it is still in the normal range, but it did nearly double.
Should I be worried about a CA125 increase?
Any increase in the CA125 is a worry. Several women on Inspire have had recurrences while their numbers were well under the ‘normal’ range. When it goes up, it’s scary no matter what the number because we are all so individualized in our response to the blood test. Some even recur when their numbers stay stable.
How long does it take for serum CA125 to return to normal?
Comparing patients in whom serum CA125 decreased to normal within a month with those that took more than a month, the median PFS was 45 and 38 months, respectively, P = 0.047, a statistically significant difference. The median OS was 56 and 38 months, respectively, P = 0.029, a statistically significant difference (see Fig. 5 ).